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Don't worry about the PP3V3_ACC line. It is only active for a very brief period of time when the phone is powered on. It is used to power devices connected in the Lightning Port.
Check PP_BATT_VACC, PP_VCC_MAIN and PP5V0_USB (when a charger is connected). Those are your main power rails. Then check the main rails coming out of the PMIC (like PP_CPU, PP_GPU, PP1V8 etc...). If you find a short, then focus on that first. Follow the schematics to identify all of the caps in the line. Inspect visually and if necessary, remove them one by one.
Don't just replace U2 for the fun of it...unless you're really good and it actually is fun :>).