It could be:
1) dead battery/batteries
2) driver not installed
3) usb dongle wasn't recognize properly due to glitch
4) drive for dongle wasn't installed correctly or corrupted for usb port its in
5) dongle radio burnt out
6) mouse radio burnt out
7) you forgot to put usb dongle in usb port.
Try fresh batteries
Try plugging the dongle in another usb port
Try unistalling then reinstalling the driver
Try going in device manager, see if there are unloaded drivers and either remove devices then refresh list; or update drivers.
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