Need some advice on why my replacement digitizer is not working

Hard to answer without more information, but a go-to answer with T100TAFs is always to check the part number on the ribbon cable. These have shipped with different digitizers for the same model. There is both a black and gold ribbon cable OEM version, then a chinese replica, then a different third party replacement with a diferent part number. You want to match it exactly, including the last 3 characters. The next suggestion I might have is to watch your screw locations. They are actually used to ground the device so if you put a black coated screw where an aluminum screw should be you get grounding issues. When you test it, if it is unresponsive try grounding your other hand to the metal case and then touching it. Sounds crazy but I have seen it behave this way.